منابع مشابه
Amiodarone-induced pulmonary toxicity
Amiodarone-induced pulmonary toxicity is a critical and potentially fatal side effect of amiodarone. Our study was designed to reveal its clinical features, including KL-6, as an interstitial marker. The medical records of eight patients (five men and three women) with amiodarone-induced pulmonary toxicity, who had been referred to our hospital, were examined. The mean age at the initiation of ...
متن کاملAmiodarone and Pulmonary Toxicity 06
Cyclophosphamide is a chemotherapeutic agent with the potential to cause pulmonary toxicity, most commonly in the form of diffuse alveolar damage. Cyclophosphamide-induced pulmonary toxicity is extremely rare and often difficult to recognize because of presence of confounding factors, including use of other cytotoxic drugs, radiation pneumonitis, oxygen toxicity, pulmonary infections, and malig...
متن کاملAcute amiodarone-induced lung toxicity
The toxic effects of amiodarone on the lung are well recognised, but the rapid onset of those effects, especially in the presence of high inspired oxygen concentrations, are perhaps not adequately appreciated. This may be a potential problem in the Intensive Care Unit (ICU) where amiodarone is frequently used in the treatment of tachydysrhythmias in patients with acute respiratory distress synd...
متن کاملHepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives.
The aim of this work was to compare hepatocellular toxicity and pharmacological activity of amiodarone (2-n-butyl-3-[3,5 diiodo-4-diethylaminoethoxybenzoyl]-benzofuran; B2-O-Et-N-diethyl) and of eight amiodarone derivatives. Three amiodarone metabolites were studied, namely, mono-N-desethylamiodarone (B2-O-Et-NH-ethyl), di-N-desethylamiodarone (B2-O-Et-NH(2)), and (2-butyl-benzofuran-3-yl)-(4-h...
متن کاملA Case of Amiodarone-Associated Pulmonary Toxicity
Amiodarone is an iodinated benzofuran derivative that represents a new and extremely effective therapy for certain life-threatening refractory cardiac arrgythmia. There are numerous side effects associated with amiodarone therapy, including corneal microdeposits. Skin reactions and others. Pulmonary toxicity, however, represents the most serious adverse reaction limiting the clinical effecacy o...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 1985
ISSN: 0025-6196
DOI: 10.1016/s0025-6196(12)60990-2